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LyGenesis’s cell therapies are engrafted using endoscopic ultrasound procedure, which is associated with decreased medical risks and costs relative to full organ transplantation. Our pipeline of therapies target a variety of unmet needs, including end stage liver disease, Type 1 diabetes, end stage renal disease, aging, and autoimmune disorder.

Welcome to LyGenesis’ Insight Corner, a place where we host blogs, videos, and external content for our audience to view and learn more about our cell therapy platform and its impact on a variety of clinical indications with large unmet needs.

Lygenesis CEO Michael Hufford speaking at Abundance360

June 8, 2023 - We were honored to have Michael invited to speak at Abundance360 this year. Watch his speech below!
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LyGenesis is Using its Cell Therapy to Combat Liver Disease

May 4, 2023 - Welcome to LyGenesis’ Insight Corner, a place where we host blogs, videos, and external content for our audience to view and learn more about our cell therapy platform and its impact on a variety of clinical indications with large unmet needs.
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Business of Biotech Podcast

Functional Ectopic Organs

April 10, 2023 - What sounds like science fiction to some is starting to look like a life changing therapy for millions of liver, kidney, pancreas, and thymus disease sufferers, LyGenesis is developing a pipeline of allogeneic cell therapies using the lymph node as an in vivo bioreactor to grow functioning ectopic organs. The science behind it is being developed not in Boston, not in Philadelphia, nor in San Franciso, but right in the heart of the rust belt in Pittsburgh, PA. This week's episode of the Business of Biotech takes us there for a conversation with LyGenesis CEO Dr. Michael Hufford, Ph.D.
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Progress, Potential And Possibilities Podcast

Advancing Novel Therapeutic Interventions For Unmet Medical Needs

November 15, 2022 - Dr. Michael Hufford, Ph.D. is the Co-Founder and the Chief Executive Officer of LyGenesis, a clinical-stage cell therapy company that transforms patient’s lymph nodes into bioreactors capable of growing functioning ectopic organs.
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Pittsburgh Region Video

LyGenesis is Pioneering Organ Regeneration in Pittsburgh

July 26, 2021 - Lygenesis, a University of Pittsburgh life sciences spinout, is using cell therapy technology to transform the methodology behind the science of organ transplantation, thanks to experts like Michael Hufford.
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The Incrementalist Podcast

Grow Your Own Organs with Michael Hufford, LyGenesis

July 17, 2021 - Host Dr. Nick van Terheyden aka Dr. Nick talks Grow Your Own Organs, with Michael Hufford, CEO Lygenesis. The discussion includes using the bodies own bio-reactor (lymph nodes) to grow replacement liver, recent FDA clearance to proceed to human trials, and how one donated liver could mean 70+ patients transplants.
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